EG.5 Covid ‘Eris’ Now Dominant Strain in US. Hospitalizations Increase…

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In the ever-evolving landscape of the COVID-19 pandemic, the emergence of new variants has become a recurring theme. The latest to grab headlines is the EG.5 subvariant. But what is it, and why should we care?

The world has been grappling with the challenges posed by these variants, each bringing its own set of concerns. As we navigate this new phase of the pandemic, understanding EG.5 becomes crucial.

The Genesis of EG.5

A Brief History of COVID-19 Variants

From the original strain identified in Wuhan, China, the SARS-CoV-2 virus has undergone numerous mutations. Some of these mutations have led to the emergence of new variants, each with its own set of characteristics. These variants, from Alpha to Delta and now Omicron, have shaped the course of the pandemic in various ways.

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The Omicron variant, in particular, alarmed global health officials due to its numerous mutations. Since its discovery, it has splintered into several subvariants, with EG.5 being one of the latest to gain attention.

The Birth of Omicron and its Offspring

The Omicron variant, first identified in South Africa, spread rapidly across the globe. Its high number of mutations raised concerns about vaccine efficacy and the potential for increased transmission or severity. As with all viruses, further mutations led to the emergence of subvariants.

EG.5, sometimes referred to as “Eris” on social media, has now become a significant player in the pandemic’s narrative. Its rise to dominance in certain regions has prompted renewed efforts to study its characteristics and implications.

The Characteristics of EG.5

How It Spreads

EG.5’s rise to dominance suggests it might possess a higher transmission rate than its predecessors. This could be due to various factors, including mutations that allow it to bind more effectively to human cells or evade neutralizing antibodies. The exact mechanisms of its spread, and how it compares to other variants, remain areas of active research.

Understanding the transmission dynamics of EG.5 is crucial for public health strategies. If it proves to be more transmissible, measures such as mask mandates, social distancing, and vaccination campaigns may need to be adjusted accordingly.

Symptoms and Severity

Early indications suggest that the symptoms of EG.5 align with those of other Omicron subvariants: fever, cough, fatigue, muscle aches, and headache. However, as with all new variants, it’s crucial to monitor for any deviations or unique symptoms associated with this subvariant.

While comprehensive data on EG.5’s symptomatology is still emerging, the global health community remains vigilant. Tracking its symptoms, severity, and any long-term effects will be crucial in the coming months.

Hospitalizations and the EG.5 Variant

Recent Trends in Hospitalizations

Weekly COVID-19 hospitalizations have seen a notable increase in recent times. According to data from the Centers for Disease Control and Prevention (CDC), hospitalizations have risen by more than 12% across the country. Specifically, for the week of July 22, the CDC reported at least 8,035 hospital admissions of patients diagnosed with COVID-19. This is an increase from the 7,165 reported during the week before. Another metric to consider is the percentage of emergency room visits related to COVID-19. As of July 28, an average of 0.92% of the past week’s emergency room visits were due to COVID-19, a rise from 0.51% through June 28.

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These figures come after a period of slowing COVID-19 trends nationwide since the last wave of infections over the winter. This marks the most significant percentage increases in these key indicators of the virus since December. Kathleen Conley, a CDC spokesperson, mentioned on July 25 that while “U.S. COVID-19 rates are still near historic lows after 7 months of steady declines,” early indicators of COVID-19 activity, such as emergency department visits and test positivity, have shown an increase in hospitalizations in the past week.

Comparing Hospitalizations to Previous Years

For context, it’s essential to compare these numbers to previous years. In 2022, hospitalizations peaked over the summer with 44,728 admissions for the week of July 23, 2022, following a wave of Omicron infections. This was nearly 12,000 more admissions compared to the rate seen a month prior. In 2021, driven by the Delta variant, hospitalizations surged, reaching 32,850 hospitalized patients by July 24, 2021. This was an increase of 20,029 more from June to July.

While the current indicators of the virus are trending upwards, hospitalizations remain far below the levels recorded at this time in previous years. The U.S. is currently averaging 1,729 more admissions per week compared to a month prior. However, it’s worth noting that the U.S. has experienced increases in COVID-19 during the past three summers, so a seasonal uptick is not entirely unexpected.

The Global Response to EG.5

Monitoring and Data Collection

Accurate data is the backbone of any public health response. However, with the end of the national public health emergency for COVID-19 earlier this year in some regions, viral data collection has become less comprehensive. This poses challenges in assessing the true prevalence and impact of EG.5.

Despite these challenges, global health organizations continue to collaborate, sharing data and insights. Genomic surveillance remains a top priority, ensuring that any new mutations or variants are quickly identified and studied.

Vaccine Adjustments

Pharmaceutical companies are in a constant race against the virus. As new variants emerge, there’s a need to adjust vaccine formulations to ensure maximum efficacy. The upcoming boosters, for instance, target the XBB.1.5 subvariant but may still offer protection against EG.5 due to the strains’ similarities.

The adaptability of vaccine platforms, especially mRNA vaccines, offers hope. As we gather more data on EG.5, vaccine formulations can be tweaked to provide the best possible protection against this and future variants.

Implications for the Future

The Ongoing Battle Against COVID-19

The emergence of EG.5 underscores the dynamic nature of the COVID-19 pandemic. As long as the virus continues to spread, it will continue to mutate, leading to the potential emergence of new variants. This ongoing battle requires a global, coordinated response, adapting to new challenges as they arise.

While the future remains uncertain, the lessons learned from previous variants provide a roadmap. By understanding the characteristics of new variants quickly, the global community can adjust strategies to minimize their impact.

Preparing for the Unknown

The COVID-19 pandemic has been a lesson in expecting the unexpected. As we look to the future, it’s clear that vigilance, flexibility, and collaboration will be key. Whether it’s adjusting public health guidelines, ramping up vaccination campaigns, or investing in research, preparedness is crucial.

The emergence of EG.5 is a reminder of the challenges ahead. However, with a global community united in its response, there’s hope that we can navigate these challenges and work towards a safer, healthier future.


The EG.5 subvariant serves as a stark reminder that the fight against COVID-19 is far from over. While challenges lie ahead, the global community’s collective experience over the past few years positions us well to face future hurdles. Through continued research, collaboration, and public health vigilance, we can hope to stay one step ahead of the virus and work towards a world free from the shadow of COVID-19.